Not All Hydrogels Are Created Equal

Arthramid Vet joint injection and box

ArthramidVet® 2.5% iPAAG Hydrogel is a pioneering treatment. Implanted into the joint itself, rather than simply masking pain, it defies conventional treatments by restoring the joints health and function.

2.5% iPAAG (intra-articular polyacrylamide hydrogel), is created by a unique patented process called IL-X cross-linking which affords clear differences in composition, manufacturing and injection techniques as well as its ability to interact with surrounding tissues.

Ultimately these characteristics determine the safety and effectiveness of Arthramid Vet®.

As a cutting edge treatment, ArthramidVet® is trusted by owners, veterinary professionals and trainers alike.

Why Use ArthramidVet® 2.5% iPAAG?

Arthramid Vet 2.5% iPAAG is a unique and patented hydrogel consisting of 97.5% sterile water and 2.5% polyacrylamide (PAAG). This results in a gel although similar to hyaluronic acid in structure and tissue compatibility, but with a superior and longer lasting effects. It integrates into the joint itself and is non-degradable.

Arthramid Vet is elastic and viscous in nature, ideally suited for injection into the joints of animals providing an innovative and safe solution to veterinarians. It is supplied in a sterile pre-filled 1ml syringe sealed with a Luer lock fitting.

Arthramid Vet is used to treat non-infectious causes of joint pain and lameness in animals, including both early and late stages of osteoarthritis (OA). OA can be caused by traumatic injury or usual wear and tear which causes the joint to become inflamed. As the cartilage or cushion between the joints breaks down, pain, stiffness, and swelling develop, causing lameness.

Lameness remains a common cause of poor performance in the equine industry. In addition to treating pain, treatment should ideally also serve to arrest or slow the progression of the disease. It is now well recognised that the OA disease process starts in the synovial membrane and that inflamed synovium is an essential component in the pathogenesis, with it always being present in cases of arthritis.

As part of the OA complex, the elastic and viscous nature of the synovial fluid is abnormally low. Furthermore, the synovial membrane becomes a source of inflammatory products (pro-inflammatory cytokines) which contribute to the progressive degrading of the joint over time.

Studies have shown Arthramid Vet integrates into the synovial membrane, stabilising the joint capsule and increasing elasticity, which in turn reduces the onset of synovitis and its harmful effects. The formation of a rejuvenated synovium further improves the nature of the synovial fluid within the joint itself.

Arthramid Vet essentially provides joint lubrication and causes a ‘cushion-like’ effect on the joint, increasing glide and which allows for the preservation and even regeneration of the joint itself contributing to reducing the pain of synovitis and osteoarthritis, and ultimately restoring the joint to healthy function (homeostasis).

Testimonials

Dr Florent David

EQUINE VETERINARY MEDICAL CENTRE

AL SHAQAB STREET, DOHA, QATAR

Arthramid Vet should be in the therapeutic toolbox of any equine veterinarian. ”

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Dr Florent David

EQUINE VETERINARY MEDICAL CENTRE

AL SHAQAB STREET, DOHA, QATAR

I have been using Arthramid Vet for five years. I see lame horses that I qualify as “non-responders”. The diagnosis/localisation of pain is accurate on those cases, but they do not respond to rest, and corticosteroids +/- HA intrasynovial. These represent my biggest challenge. Arthramid Vet is often of great help on those cases in association with orthopaedic shoeing, magnetic diathermy and a revisited exercise program to regain and maintain soundness.

The second set of cases that represent a challenge are horses presented with poor performance. They are not genuinely lame, but several sites in their body including joints show signs of wear and tear. This accumulation of stress is associated with the athletic activity they perform and also to some individual predispositions to injury (poor conformation, overweight, lack of repair capacities). On these cases, Arthramid Vet for its long duration of action can help.

The third group of horses I see as a challenge are diagnosed with soft tissue injuries within synovial structures (tendon sheath, bursa or joint). In general, the body responds poorly to healing those lesions. It is still unclear to me if Arthramid Vet can help to return some of these horses to soundness when unsatisfactory healing of intrasynovial soft tissue has occurred.

Arthramid Vet is a very potent and very safe drug to use, and I recommend it to my clients and other vets. Arthramid Vet should be in the therapeutic toolbox of any equine veterinarian. I see Arthramid Vet as a solution with great potential, and more work is needed to refine its use.

Arthramid Vet should be in the therapeutic toolbox of any equine veterinarian. ”

Dr Emma Wood

VETERINARIAN

On his non gallop days he would complete 4000m of cantering daily, this is a lot of miles on his joints and I do not believe we could have kept him sound without the use of Arthramid.”

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Dr Emma Wood

VETERINARIAN

We treated Sound (front fetlocks) in December 2019 which correlates with his turn around in form in February and March 2020, he was again treated in June 2020 (front fetlocks) and July 2020 (left front tendon sheath) after a flare of synovitis. Within 3 weeks both fetlocks and tendon sheath were tight and his action terrific. He went on to run 2nd in the Lexus and win the G2 Zipping Classic (5+ months after injection). As an 8yo stallion Sound tends to hold condition and to reach peak fitness he underwent a tough spring training campaign. On his non gallop days he would complete 4000m of cantering daily, this is a lot of miles on his joints and I do not believe we could have kept him sound without the use of Arthramid. Not only did he perform well but he maintained soundness and his action improved throughout the preparation.

On his non gallop days he would complete 4000m of cantering daily, this is a lot of miles on his joints and I do not believe we could have kept him sound without the use of Arthramid.”

ALL TESTIMONIALS

Precision Medicine

  • Studies show over 82.5% of horses respond after treatment have a successful resolution of joint lameness.
  • Meets Animal Welfare Concerns; Arthramid Vet is not simply a lubricant or painkiller. It’s a unique biomedical technology that helps heal and restore the joint to healthy function.
  • Made to Last; When compared to traditional treatments for joint lameness, research shows that Arthramid Vet is better and lasts longer with proven efficacy for up to 1- 2 years.
  • One of A Kind; Arthramid Vet’s unique and patented IL-X Cross-Linking technology produced in a European Certified facility makes it the only safe and most effective 2.5% intra-articular polyacrylamide (2.5% iPAAG) hydrogel available anywhere in the world.

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