Not All Hydrogels Are Created Equal
ArthramidVet® 2.5% iPAAG Hydrogel is a pioneering treatment. Implanted into the joint itself, rather than simply masking pain, it defies conventional treatments by restoring the joints health and function.
2.5% iPAAG (intra-articular polyacrylamide hydrogel), is created by a unique patented process called IL-X cross-linking which affords clear differences in composition, manufacturing and injection techniques as well as its ability to interact with surrounding tissues.
Ultimately these characteristics determine the safety and effectiveness of Arthramid Vet®.
As a cutting edge treatment, ArthramidVet® is trusted by owners, veterinary professionals and trainers alike.
Why Use ArthramidVet® 2.5% iPAAG?
Arthramid Vet 2.5% iPAAG is a unique and patented hydrogel consisting of 97.5% sterile water and 2.5% polyacrylamide (PAAG). This results in a gel although similar to hyaluronic acid in structure and tissue compatibility, but with a superior and longer lasting effects. It integrates into the joint itself and is non-degradable.
Arthramid Vet is elastic and viscous in nature, ideally suited for injection into the joints of animals providing an innovative and safe solution to veterinarians. It is supplied in a sterile pre-filled 1ml syringe sealed with a Luer lock fitting.
Arthramid Vet is used to treat non-infectious causes of joint pain and lameness in animals, including both early and late stages of osteoarthritis (OA). OA can be caused by traumatic injury or usual wear and tear which causes the joint to become inflamed. As the cartilage or cushion between the joints breaks down, pain, stiffness, and swelling develop, causing lameness.
Lameness remains a common cause of poor performance in the equine industry. In addition to treating pain, treatment should ideally also serve to arrest or slow the progression of the disease. It is now well recognised that the OA disease process starts in the synovial membrane and that inflamed synovium is an essential component in the pathogenesis, with it always being present in cases of arthritis.
As part of the OA complex, the elastic and viscous nature of the synovial fluid is abnormally low. Furthermore, the synovial membrane becomes a source of inflammatory products (pro-inflammatory cytokines) which contribute to the progressive degrading of the joint over time.
Studies have shown Arthramid Vet integrates into the synovial membrane, stabilising the joint capsule and increasing elasticity, which in turn reduces the onset of synovitis and its harmful effects. The formation of a rejuvenated synovium further improves the nature of the synovial fluid within the joint itself.
Arthramid Vet essentially provides joint lubrication and causes a ‘cushion-like’ effect on the joint, increasing glide and which allows for the preservation and even regeneration of the joint itself contributing to reducing the pain of synovitis and osteoarthritis, and ultimately restoring the joint to healthy function (homeostasis).
Testimonials
Dr Marc Koene
TIERKLINIK LÜSCHE GMBH EQUINE HOSPITAL
NORTHERN GERMANY
I was one of the first vets to use Arthramid worldwide and the results are quite astonishing”
Dr Marc Koene
TIERKLINIK LÜSCHE GMBH EQUINE HOSPITAL
NORTHERN GERMANY
I was one of the first vets to use Arthramid worldwide and have now used Arthramid for over 10 years in our clinic. We have injected over a thousand horses and have found it to be very safe. It has been a major game-changer in the way we treat OA in our patients. We have fantastic results with really frustrating cases and are still working on new indications and treatment schemes for the product. We are also looking into the ongoing research, especially around the Mode of Action.
There are not many “new” products implemented in our OA Toolbox in recent years. Regenerative medicine and Bisphosphonates were the greatest new assets and I rate Arthramid Vet in the same league. 2.5% PAAG gives us the chance to minimize corticosteroids and we have no threats of “doping positive “ cases. As well, some horses, instead of being destroyed, are happily back in business. I would encourage every orthopaedic vet to try the product. They will love it, if their case selection is appropriate.
I was one of the first vets to use Arthramid worldwide and the results are quite astonishing”
Dr Florent David
EQUINE VETERINARY MEDICAL CENTRE
AL SHAQAB STREET, DOHA, QATAR
Arthramid Vet should be in the therapeutic toolbox of any equine veterinarian. ”
Dr Florent David
EQUINE VETERINARY MEDICAL CENTRE
AL SHAQAB STREET, DOHA, QATAR
I have been using Arthramid Vet for five years. I see lame horses that I qualify as “non-responders”. The diagnosis/localisation of pain is accurate on those cases, but they do not respond to rest, and corticosteroids +/- HA intrasynovial. These represent my biggest challenge. Arthramid Vet is often of great help on those cases in association with orthopaedic shoeing, magnetic diathermy and a revisited exercise program to regain and maintain soundness.
The second set of cases that represent a challenge are horses presented with poor performance. They are not genuinely lame, but several sites in their body including joints show signs of wear and tear. This accumulation of stress is associated with the athletic activity they perform and also to some individual predispositions to injury (poor conformation, overweight, lack of repair capacities). On these cases, Arthramid Vet for its long duration of action can help.
The third group of horses I see as a challenge are diagnosed with soft tissue injuries within synovial structures (tendon sheath, bursa or joint). In general, the body responds poorly to healing those lesions. It is still unclear to me if Arthramid Vet can help to return some of these horses to soundness when unsatisfactory healing of intrasynovial soft tissue has occurred.
Arthramid Vet is a very potent and very safe drug to use, and I recommend it to my clients and other vets. Arthramid Vet should be in the therapeutic toolbox of any equine veterinarian. I see Arthramid Vet as a solution with great potential, and more work is needed to refine its use.
Arthramid Vet should be in the therapeutic toolbox of any equine veterinarian. ”
Precision Medicine
- Studies show over 82.5% of horses respond after treatment have a successful resolution of joint lameness.
- Meets Animal Welfare Concerns; Arthramid Vet is not simply a lubricant or painkiller. It’s a unique biomedical technology that helps heal and restore the joint to healthy function.
- Made to Last; When compared to traditional treatments for joint lameness, research shows that Arthramid Vet is better and lasts longer with proven efficacy for up to 1- 2 years.
- One of A Kind; Arthramid Vet’s unique and patented IL-X Cross-Linking technology produced in a European Certified facility makes it the only safe and most effective 2.5% intra-articular polyacrylamide (2.5% iPAAG) hydrogel available anywhere in the world.
