ArthramidVet® is used by veterinarians everyday around the world for the treatment of joint lameness in horses. Multiple published studies from high profile institutions, and treating thousands of equine patients across all equestrian disciplines, show that ArthramidVet® is a safe and effective treatment for osteoarthritis and joint lameness in animals. Explore this page for more information and to access findings from studies of ArthramidVet® 2.5% iPAAG.
Arthramid Vet White Paper
Veterinarians: Get your copy of our 24 page white paper today, covering Treatment of Joint Lameness, Pathophysiology, Manufacturing, Mechanism of Action, Clinical Safety and Putting it into Practice.
Scientific Publications
Lowe J, de Clifford L, Julian A, Koene M. Histologic and cytologic changes in normal equine joints after injection with 2.5% injectable polyacrylamide hydrogel reveal low-level macrophage-driven foreign body response. JAVMA 2024
de Clifford, L.D., Lowe, J.N., McKellar, C.D., Bolwell, C., and David, F. (2021). A double-blinded positive control study comparing the relative efficacy of 2.5% polyacrylamide hydrogel (PAAG) against triamcinolone acetonide (TA) and sodium hyaluronate (HA) in the management of middle carpal joint lameness in racing Thoroughbreds
de Clifford, L.D., Lowe, J.N., McKellar, C.D., Bolwell, C., and David, F. (2019). Use of a 2.5% Cross-Linked Polyacrylamide Hydrogel in the Management of Joint Lameness in a Population of Flat Racing Thoroughbreds: A Pilot Study
Henrikson, M., Overgaard, A., and Bliddal, H. (2017). Initial Estimates of Efficacy of Intra-Articular 2.5% Polyacrylamide Hydrogel for the Treatment of Knee Osteoarthritis: An Observational Proof-of-Concept Study
Bathe, A.P., Read, R.M., and Briggs, C. (2016). Intra-articular polyacrylamide hydrogel for the treatment of 20 horses with non-responsive osteoarthritis of the interphalangeal joints: a prospective study
Christensen, L., Illigen, K.E., Hansen, M., Sarvaa, R., and Conogham, P.G. (2016). Synovial incorporation of polyacrylamide hydrogel after injection into normal and osteoarthritic animal joints
Tnibar et al (2015). An international multi-centre prospective study on the efficacy of an intraarticular polyacrylamide hydrogel in horses with osteoarthritis: a 24 months follow-up
Tnibar et al (2014). Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study
Janssen, I., Koene, M., and Lischer, C. (2012). Intraarticular application of polyacrylamide hydrogel as a treatment of osteoarthritis in the distal interphalangeal joint: Case series with 12 horses
Testimonials
Dr Florent David
EQUINE VETERINARY MEDICAL CENTRE
AL SHAQAB STREET, DOHA, QATAR
Arthramid Vet should be in the therapeutic toolbox of any equine veterinarian. ”
Dr Florent David
EQUINE VETERINARY MEDICAL CENTRE
AL SHAQAB STREET, DOHA, QATAR
I have been using Arthramid Vet for five years. I see lame horses that I qualify as “non-responders”. The diagnosis/localisation of pain is accurate on those cases, but they do not respond to rest, and corticosteroids +/- HA intrasynovial. These represent my biggest challenge. Arthramid Vet is often of great help on those cases in association with orthopaedic shoeing, magnetic diathermy and a revisited exercise program to regain and maintain soundness.
The second set of cases that represent a challenge are horses presented with poor performance. They are not genuinely lame, but several sites in their body including joints show signs of wear and tear. This accumulation of stress is associated with the athletic activity they perform and also to some individual predispositions to injury (poor conformation, overweight, lack of repair capacities). On these cases, Arthramid Vet for its long duration of action can help.
The third group of horses I see as a challenge are diagnosed with soft tissue injuries within synovial structures (tendon sheath, bursa or joint). In general, the body responds poorly to healing those lesions. It is still unclear to me if Arthramid Vet can help to return some of these horses to soundness when unsatisfactory healing of intrasynovial soft tissue has occurred.
Arthramid Vet is a very potent and very safe drug to use, and I recommend it to my clients and other vets. Arthramid Vet should be in the therapeutic toolbox of any equine veterinarian. I see Arthramid Vet as a solution with great potential, and more work is needed to refine its use.
Arthramid Vet should be in the therapeutic toolbox of any equine veterinarian. ”
Dr Emma Wood
VETERINARIAN
On his non gallop days he would complete 4000m of cantering daily, this is a lot of miles on his joints and I do not believe we could have kept him sound without the use of Arthramid.”
Dr Emma Wood
VETERINARIAN
We treated Sound (front fetlocks) in December 2019 which correlates with his turn around in form in February and March 2020, he was again treated in June 2020 (front fetlocks) and July 2020 (left front tendon sheath) after a flare of synovitis. Within 3 weeks both fetlocks and tendon sheath were tight and his action terrific. He went on to run 2nd in the Lexus and win the G2 Zipping Classic (5+ months after injection). As an 8yo stallion Sound tends to hold condition and to reach peak fitness he underwent a tough spring training campaign. On his non gallop days he would complete 4000m of cantering daily, this is a lot of miles on his joints and I do not believe we could have kept him sound without the use of Arthramid. Not only did he perform well but he maintained soundness and his action improved throughout the preparation.
On his non gallop days he would complete 4000m of cantering daily, this is a lot of miles on his joints and I do not believe we could have kept him sound without the use of Arthramid.”
